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Importin α3/Qip1 Is Involved in Multiplication of Mutant Influenza Virus with Alanine Mutation at Amino Acid 9 Independently of Nuclear Transport Function

The nucleoprotein (NP) of influenza A virus is transported into the nucleus via the classical importin α/β pathway, and proceeds via nuclear localization signals (NLSs) recognized by importin α molecules. Although NP binds to importin α isoforms Rch1, Qip1 and NPI-1, the role of each individual isof...

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Detalhes bibliográficos
Main Authors: Sasaki, Yutaka, Hagiwara, Kyoji, Kakisaka, Michinori, Yamada, Kazunori, Murakami, Tomoyuki, Aida, Yoko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559588/
https://ncbi.nlm.nih.gov/pubmed/23383277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055765
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