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Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage

Apoptosis, autophagy, necrosis and cellular senescence are key responses of cells that were exposed to genotoxicants. The types of DNA damage triggering these responses and their interrelationship are largely unknown. Here we studied these responses in glioma cells treated with the methylating agent...

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Detalhes bibliográficos
Main Authors: Knizhnik, Anna V., Roos, Wynand P., Nikolova, Teodora, Quiros, Steve, Tomaszowski, Karl-Heinz, Christmann, Markus, Kaina, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559438/
https://ncbi.nlm.nih.gov/pubmed/23383259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055665
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