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Down-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant Mice

Pregnancy increases the urinary excretion of chemicals in women and rodents. It is unknown whether the enhanced clearance of drugs during pregnancy involves changes in the expression of transporters that mediate chemical secretion and reabsorption. The purpose of this study was to quantify the mRNA...

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Detalhes bibliográficos
Main Authors: Yacovino, Lindsay L., Gibson, Christopher J., Aleksunes, Lauren M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558863/
https://ncbi.nlm.nih.gov/pubmed/22896729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.047092
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