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Studies of (±)-3,4-Methylenedioxymethamphetamine (MDMA) Metabolism and Disposition in Rats and Mice: Relationship to Neuroprotection and Neurotoxicity Profile

The neurotoxicity of (±)-3,4-methylenedioxymethamphetamine (MDMA; “Ecstasy”) is influenced by temperature and varies according to species. The mechanisms underlying these two features of MDMA neurotoxicity are unknown, but differences in MDMA metabolism have recently been implicated in both. The pre...

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Detalhes bibliográficos
Main Authors: Mueller, Melanie, Maldonado-Adrian, Concepcion, Yuan, Jie, McCann, Una D., Ricaurte, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558829/
https://ncbi.nlm.nih.gov/pubmed/23209329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201699
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