IL-18 Induces Airway Hyperresponsiveness and Pulmonary Inflammation via CD4(+) T Cell and IL-13

IL-18 plays a key role in the pathogenesis of pulmonary inflammatory diseases including pulmonary infection, pulmonary fibrosis, lung injury and chronic obstructive pulmonary disease (COPD). However, it is unknown whether IL-18 plays any role in the pathogenesis of asthma. We hypothesized that overe...

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Autors principals: Sawada, Masanori, Kawayama, Tomotaka, Imaoka, Haruki, Sakazaki, Yuki, Oda, Hanako, Takenaka, Shin-ichi, Kaku, Yoichiro, Azuma, Koichi, Tajiri, Morihiro, Edakuni, Nobutaka, Okamoto, Masaki, Kato, Seiya, Hoshino, Tomoaki
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558507/
https://ncbi.nlm.nih.gov/pubmed/23382928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054623
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