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Phenytoin Inhibits the Persistent Sodium Current in Neocortical Neurons by Modifying Its Inactivation Properties
The persistent Na(+) current (I(NaP)) is important for neuronal functions and can play a role in several pathologies, although it is small compared to the transient Na(+) current (I(NaT)). Notably, I(NaP) is not a real persistent current because it undergoes inactivation with kinetics in the order o...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558486/ https://ncbi.nlm.nih.gov/pubmed/23383157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055329 |
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