Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes

BACKGROUND: The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of middle-aged ovariectomized rats, but not in young one...

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Autors principals: Sárvári, Miklós, Hrabovszky, Erik, Kalló, Imre, Solymosi, Norbert, Likó, István, Berchtold, Nicole, Cotman, Carl, Liposits, Zsolt
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558453/
https://ncbi.nlm.nih.gov/pubmed/23206327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-264
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