The Protein Kinase Snf1 Is Required for Tolerance to the Ribonucleotide Reductase Inhibitor Hydroxyurea

The Snf1/AMP-activated kinases are involved in a wide range of stress responses in eukaryotic cells. We discovered a novel role for the Snf1 kinase in the cellular response to genotoxic stress in yeast. snf1 mutants are hypersensitive to hydroxyurea (HU), methyl-methane sulfonate, and cadmium, but t...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Dubacq, Caroline, Chevalier, Anne, Mann, Carl
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2004
Assuntos:	Cell Growth and Development
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC355840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14993292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.6.2560-2572.2004
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