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Elongation Inhibition by DRB Sensitivity-Inducing Factor Is Regulated by the A20 Promoter via a Novel Negative Element and NF-κB

A20 is an immediate-early NF-κB target gene. Prior to NF-κB stimulation, the A20 promoter is bound by the polymerase II machinery to allow rapid transcription activation. Here we show that the basal A20 transcription is repressed at the level of elongation in a promoter-specific fashion. Immunodeple...

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Udgivet i:Mol Cell Biol
Principais autores: Ainbinder, Elena, Amir-Zilberstein, Liat, Yamaguchi, Yuki, Handa, Hiroshi, Dikstein, Rivka
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC355833/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14993282/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.6.2444-2454.2004
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