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Complement mediated hepatocytes injury in a model of autoantibody induced hepatitis

Despite multiple reports on autoantibody-initiated complement activation in autoimmune hepatitis (AIH), how does the humoral immunity contribute to the pathogenesis of AIH remained unclear. In this report, by adoptively transferring a polyclonal rabbit anti-OVA antibody into Hep-OVA Tg mice in which...

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Detalhes bibliográficos
Main Authors: Tu, Zhidan, Li, Qing, Chou, Hong-Shiue, Hsieh, Ching-Chuang, Meyerson, Howard, Peters, Marion G., Bu, Hong, Fung, John J, Qian, Shiguang, Lu, Lina, Lin, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557916/
https://ncbi.nlm.nih.gov/pubmed/20851495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2010.08.004
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