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High immunogenicity of nicotine vaccines obtained by intradermal delivery with safe adjuvants

Immunotherapy for tobacco addiction may offer a safe, alternative treatment if the immunogenicity of the current nicotine vaccines can be improved. We show here that intradermal (ID) immunization induces the production of antibody directed against nicotine (NicAb) at a much higher level than convent...

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Библиографические подробности
Главные авторы: Chen, Xinyuan, Pravetoni, Marco, Bhayana, Brijesh, Pentel, Paul R., Wu, Mei X.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557791/
https://ncbi.nlm.nih.gov/pubmed/23123021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.10.069
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