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Crystal Structure of Decaprenylphosphoryl-β-D-Ribose 2’-Epimerase from Mycobacterium smegmatis

Decaprenylphosphoryl-β-D-ribose 2’-epimerase (DprE1) is an essential enzyme in the biosynthesis of cell wall components and a target for development of anti-tuberculosis drugs. We determined the crystal structure of a truncated form of DprE1 from Mycobacterium smegmatis in two crystal forms to up to...

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Bibliografiske detaljer
Main Authors: Li, Hua, Jogl, Gerwald
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557725/
https://ncbi.nlm.nih.gov/pubmed/23184707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24220
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