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L1CAM and its cell-surface mutants: new mechanisms and effects relevant to the physiology and pathology of neural cells
The L1 syndrome, a genetic disease that affects 1/30 000 newborn males, is sustained by numerous missense mutations of L1 cell adhesion molecule (L1CAM), an adhesion surface protein active also in transmembrane signaling, essential for the development and function of neurons. To investigate the cell...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557714/ https://ncbi.nlm.nih.gov/pubmed/22973895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12015 |
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