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L1CAM and its cell-surface mutants: new mechanisms and effects relevant to the physiology and pathology of neural cells

The L1 syndrome, a genetic disease that affects 1/30 000 newborn males, is sustained by numerous missense mutations of L1 cell adhesion molecule (L1CAM), an adhesion surface protein active also in transmembrane signaling, essential for the development and function of neurons. To investigate the cell...

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Bibliografske podrobnosti
Main Authors: Tagliavacca, Luigina, Colombo, Federico, Racchetti, Gabriella, Meldolesi, Jacopo
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557714/
https://ncbi.nlm.nih.gov/pubmed/22973895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12015
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