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The fusion loops and membrane proximal region of Epstein-Barr virus glycoprotein B (gB) can function in the context of herpes simplex virus 1 gB when substituted individually but not in combination

Among the herpesvirus glycoprotein B (gB) fusion proteins, the hydrophobic content of fusion loops and membrane proximal regions (MPR) are inversely correlated with each other. We examined the functional importance of the hydrophobicity of these regions by replacing them in herpes simplex virus type...

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Autori principali: Zago, Anna, Connolly, Sarah A., Spear, Patricia G., Longnecker, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557662/
https://ncbi.nlm.nih.gov/pubmed/23089849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2012.10.015
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