Targeting Oxidative Stress Injury after Ischemic Stroke in Conscious Rats: Limited Benefits with Apocynin Highlight the Need to Incorporate Long Term Recovery

NADPH oxidase is a major source of superoxide anion following stroke and reperfusion. This study evaluated the effects of apocynin, a known antioxidant and inhibitor of Nox2 NADPH, on neuronal injury and cell-specific responses to stroke induced in the conscious rat. Apocynin treatment (50 mg/kg i.p...

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Detalhes bibliográficos
Principais autores: Weston, Robert M., Lin, Bin, Dusting, Gregory J., Roulston, Carli L.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557625/
https://ncbi.nlm.nih.gov/pubmed/23401848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/648061
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