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Residue-Specific Membrane Location of Peptides and Proteins Using Specifically and Extensively Deuterated Lipids and 13C-2H Rotational-Echo Double-Resonance Solid-State NMR
Residue-specific location of peptides in the hydrophobic core of membranes was examined using 13C-2H REDOR and samples in which the lipids were selectively deuterated. The transmembrane topology of the KALP peptide was validated with this approach with substantial dephasing observed for deuteration...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557618/ https://ncbi.nlm.nih.gov/pubmed/23225071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-012-9692-8 |
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