Acinetobacter baumannii rOmpA Vaccine Dose Alters Immune Polarization and Immunodominant Epitopes

BACKGROUND: The rOmpA vaccine has been shown to protect mice from lethal infection caused by extreme-drug-resistant (XDR) Acinetobacter baumannii. The role of dose in immunology of the rOmpA vaccine was explored. METHODS: Mice were vaccinated with various doses of rOmpA plus aluminum hydroxide (Al(O...

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Hauptverfasser: Lin, Lin, Tan, Brandon, Pantapalangkoor, Paul, Ho, Tiffany, Hujer, Andrea M., Taracila, Magdalena A., Bonomo, Robert A., Spellberg, Brad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557524/
https://ncbi.nlm.nih.gov/pubmed/23153442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.11.008
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