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Increased transcription in hydroxyurea-treated root meristem cells of Vicia faba

Hydroxyurea (HU), an inhibitor of ribonucleotide reductase, prevents cells from progressing through S phase by depletion of deoxyribonucleoside triphosphates. Concurrently, disruption of DNA replication leads to double-strand DNA breaks. In root meristems of Vicia faba, HU triggers cell cycle arrest...

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Detalhes bibliográficos
Main Authors: Winnicki, Konrad, Polit, Justyna Teresa, Maszewski, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557396/
https://ncbi.nlm.nih.gov/pubmed/22526201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00709-012-0402-x
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