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Brain penetration of the OAB drug trospium chloride is not increased in aged mice
PURPOSE: To analyse whether the permeability of the blood–brain barrier to the antimuscarinic drug trospium chloride is altered with ageing. This is a relevant question for elderly patients with overactive bladder syndrome who are treated with trospium chloride as the occurrence of adverse effects o...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557395/ https://ncbi.nlm.nih.gov/pubmed/22120415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00345-011-0803-z |
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