Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1

Mesalamine (5-ASA) is widely used for the treatment of ulcerative colitis, a remitting condition characterized by chronic inflammation of the colon. Knowledge about the molecular and cellular targets of 5-ASA is limited and a clear understanding of its activity in intestinal homeostasis and interfer...

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Autors principals: Khare, Vineeta, Lyakhovich, Alex, Dammann, Kyle, Lang, Michaela, Borgmann, Melanie, Tichy, Boris, Pospisilova, Sarka, Luciani, Gloria, Campregher, Christoph, Evstatiev, Rayko, Pflueger, Maren, Hundsberger, Harald, Gasche, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557386/
https://ncbi.nlm.nih.gov/pubmed/23146664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.10.026
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