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Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis
BACKGROUND: Leukotrienes are potent inflammatory mediators, which in a number of studies have been found to be associated with ischemic stroke pathology: gene variants affecting leukotriene synthesis, including the FLAP (ALOX5AP) gene, have in human studies shown correlation to stroke incidence, and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557197/ https://ncbi.nlm.nih.gov/pubmed/23194405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-146 |
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