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Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer

BACKGROUND: G-protein-coupled estrogen receptor (GPER/GPR30) was reported to bind 17β-estradiol (E(2)), tamoxifen, and ICI 182,780 (fulvestrant) and promotes activation of epidermal growth factor receptor (EGFR)-mediated signaling in breast, endometrial and thyroid cancer cells. Although lung adenoc...

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Detalhes bibliográficos
Main Authors: Jala, Venkatakrishna Rao, Radde, Brandie N, Haribabu, Bodduluri, Klinge, Carolyn M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557142/
https://ncbi.nlm.nih.gov/pubmed/23273253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-624
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