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Ibuprofen Inhibits Colitis-Induced Overexpression of Tumor-Related Rac1b

The serrated pathway to colorectal tumor formation involves oncogenic mutations in the BRAF gene, which are sufficient for initiation of hyperplastic growth but not for tumor progression. A previous analysis of colorectal tumors revealed that overexpression of splice variant Rac1b occurs in around 8...

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Huvudupphovsmän: Matos, Paulo, Kotelevets, Larissa, Goncalves, Vania, Henriques, Andreia, Zerbib, Philippe, Moyer, Mary Pat, Chastre, Eric, Jordan, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press Inc. 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556943/
https://ncbi.nlm.nih.gov/pubmed/23359345
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