The combined use of paclitaxel-loaded nanoparticles with a low-molecular-weight copolymer inhibitor of P-glycoprotein to overcome drug resistance

Two types of nanoparticles were prepared using the diblock copolymer methoxy poly(ethylene glycol)-block-poly(caprolactone) (MePEG-b-PCL), with either a short PCL block length, which forms micelles, or with a longer PCL block length, which forms kinetically “frozen core” structures termed nanosphere...

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Main Authors: Wan, Chung Ping Leon, Letchford, Kevin, Jackson, John K, Burt, Helen M
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2013
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556923/
https://ncbi.nlm.nih.gov/pubmed/23378760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S38737
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