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Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing

It has become increasingly apparent that one of the major hurdles in the genomic age will be the bioinformatics challenges of next-generation sequencing. We provide an overview of a general framework of bioinformatics analysis. For each of the three stages of (1) alignment, (2) variant calling, and...

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Hlavní autoři: Dolled-Filhart, Marisa P., Lee, Michael, Ou-yang, Chih-wen, Haraksingh, Rajini Rani, Lin, Jimmy Cheng-Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556895/
https://ncbi.nlm.nih.gov/pubmed/23365548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/730210
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