Safety and Efficacy of 188-Rhenium-Labeled Antibody to Melanin in Patients with Metastatic Melanoma

There is a need for effective “broad spectrum” therapies for metastatic melanoma which would be suitable for all patients. The objectives of Phase Ia/Ib studies were to evaluate the safety, pharmacokinetics, dosimetry, and antitumor activity of (188)Re-6D2, a 188-Rhenium-labeled antibody to melanin....

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Autores principales: Klein, M., Lotem, M., Peretz, T., Zwas, S. T., Mizrachi, S., Liberman, Y., Chisin, R., Schachter, J., Ron, I. G., Iosilevsky, G., Kennedy, J. A., Revskaya, E., de Kater, A. W., Banaga, E., Klutzaritz, V., Friedmann, N., Galun, E., DeNardo, G. L., DeNardo, S. J., Casadevall, A., Dadachova, E., Thornton, G. B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2013
Materias:
Clinical Study
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556872/
https://ncbi.nlm.nih.gov/pubmed/23365757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/828329
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