Analysis of SOX2 expression in developing human testis and germ cell neoplasia

The transcriptional regulators of pluripotency, POU5F1 (OCT4), NANOG and SOX2, are highly expressed in embryonal carcinoma (EC). In contrast to OCT4 and NANOG, SOX2 has not been demonstrated in the early human germ cell lineage or carcinoma in situ (CIS), the precursor for testicular germ cell tumou...

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Main Authors: SONNE, SI B., PERRETT, REBECCA M., NIELSEN, JOHN E., BAXTER, MELISSA A., KRISTENSEN, DAVID M., LEFFERS, HENRIK, HANLEY, NEIL A., RAJPERT-DE-MEYTS, EWA
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556811/
https://ncbi.nlm.nih.gov/pubmed/19876845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1387/ijdb.082668ss
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