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Innate Sensing of HIV-1 Assembly by Tetherin Induces NFκB-Dependent Proinflammatory Responses

Antiviral proteins that recognize pathogen-specific or aberrantly located molecular motifs are perfectly positioned to act as pattern-recognition receptors and signal to the immune system. Here we investigated whether the interferon-induced viral restriction factor tetherin (CD317/BST2), which is kn...

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Detalhes bibliográficos
Main Authors: Galão, Rui Pedro, Le Tortorec, Anna, Pickering, Suzanne, Kueck, Tonya, Neil, Stuart J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556742/
https://ncbi.nlm.nih.gov/pubmed/23159053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.10.007
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