An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva

Fibrodysplasia ossificans progressiva (FOP; MIM #135100) is a debilitating genetic disorder of dysregulated cellular differentiation characterized by malformation of the great toes during embryonic skeletal development and by progressive heterotopic endochondral ossification post-natally. Patients w...

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Autori principali: Chakkalakal, Salin A., Zhang, Deyu, Culbert, Andria L., Convente, Michael R., Caron, Robert J., Wright, Alexander C., Maidment, Andrew D.A., Kaplan, Frederick S., Shore, Eileen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556640/
https://ncbi.nlm.nih.gov/pubmed/22508565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1637
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