Competitive Androgen Receptor Antagonism as a Factor Determining the Predictability of Cumulative Antiandrogenic Effects of Widely Used Pesticides

Background: Many pesticides in current use have recently been revealed as in vitro androgen receptor (AR) antagonists, but information about their combined effects is lacking. Objective: We investigated the combined effects and the competitive AR antagonism of pesticide mixtures. Methods: We used th...

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Hauptverfasser: Orton, Frances, Rosivatz, Erika, Scholze, Martin, Kortenkamp, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Institute of Environmental Health Sciences 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556629/
https://ncbi.nlm.nih.gov/pubmed/23008280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1205391
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