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The fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate

Fungi produce α-aminoadipate, a precursor for penicillin and lysine via the α-aminoadipate pathway. Despite the biotechnological importance of this pathway, the essential isomerization of homocitrate via homoaconitate to homoisocitrate has hardly been studied. Therefore, we analysed the role of homo...

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Bibliographic Details
Main Authors: Fazius, Felicitas, Shelest, Ekaterina, Gebhardt, Peter, Brock, Matthias
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556520/
https://ncbi.nlm.nih.gov/pubmed/23106124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12076
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