Loss of dysbindin-1 in mice impairs reward-based operant learning by increasing impulsive and compulsive behavior

The dystrobrevin-binding protein 1 (DTNBP1) gene, which encodes the dysbindin-1 protein, is a potential schizophrenia susceptibility gene. Polymorphisms in the DTNBP1 gene have been associated with altered cognitive abilities. In the present study, dysbindin-1 null mutant (dys−/−), heterozygous (dys...

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Bibliographic Details
Main Authors: Carr, Gregory V., Jenkins, Kimberly A., Weinberger, Daniel R., Papaleo, Francesco
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556458/
https://ncbi.nlm.nih.gov/pubmed/23261874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2012.12.021
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