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HIV Immune Complexes Prevent Excitotoxicity by Interaction with NMDA Receptors

PURPOSE: Human immunodeficiency virus-1 (HIV)-associated neurocognitive disorder (HAND) is a neurodegenerative disease for which there is no available neuroprotective therapy. Viral proteins, such as Tat, have been implicated as agents of neurotoxicity via multiple mechanisms, including effects by d...

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Detalhes bibliográficos
Main Authors: Rumbaugh, Jeffrey A., Bachani, Muznabanu, Li, Wenxue, Butler, Tracy R., Smith, Katherine J., Bianchet, Mario A., Wang, Tongguang, Prendergast, Mark A., Sacktor, Ned, Nath, Avindra
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556339/
https://ncbi.nlm.nih.gov/pubmed/22940423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.08.013
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