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M2/M1 Ratio of Tumor Associated Macrophages and PPAR-gamma Expression in Uveal Melanomas with Class 1 and Class 2 Molecular Profiles

Macrophages have been found to be negative predictors of outcome in patients with uveal melanoma. In particular, recent studies point towards a disease-progressing role of proangiogenic M2 macrophages in melanomas with monosomy 3. Although most studies implicate a protective effect of PPAR-gamma act...

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Detalhes bibliográficos
Main Authors: Herwig, Martina C., Bergstrom, Chris, Wells, Jill R., Höller, Tobias, Grossniklaus, Hans E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556238/
https://ncbi.nlm.nih.gov/pubmed/23206928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.11.012
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