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Isobutylhydroxyamides from the Pericarp of Nepalese Zanthoxylum armatum Inhibit NF1-defective Tumor Cell Line Growth

A neurofibromatosis type 1 (NF1) based bioassay-guided phytochemical investigation on Zanthoxylum armatum collected in Nepal led to the isolation of four new timuramides A-D (1-4) and six known sanshools (5-10). The structures of all compounds were established by using modern spectroscopic technique...

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Detalhes bibliográficos
Main Authors: Devkota, Krishna P., Wilson, Jennifer, Henrich, Curtis J., McMahon, James B., Reilly, Karlyne M., Beutler, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556213/
https://ncbi.nlm.nih.gov/pubmed/23268719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np300696g
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