Inhibition of IL-17A in Tumor Microenvironment Augments Cytotoxicity of Tumor-Infiltrating Lymphocytes in Tumor-Bearing Mice

It remains controversial whether IL-17A promotes or inhibits cancer progression. We hypothesized that IL-17A that is locally produced in the tumor microenvironment has an important role in angiogenesis and tumor immunity. We investigated the effect of inhibiting IL-17A at tumor sites on tumor growth...

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Main Authors: Hayata, Keiji, Iwahashi, Makoto, Ojima, Toshiyasu, Katsuda, Masahiro, Iida, Takeshi, Nakamori, Mikihito, Ueda, Kentaro, Nakamura, Masaki, Miyazawa, Motoki, Tsuji, Toshiaki, Yamaue, Hiroki
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556079/
https://ncbi.nlm.nih.gov/pubmed/23372655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053131
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