Overexpression of aldo-keto-reductase in azole-resistant clinical isolates of Candida glabrata determined by cDNA-AFLP

BACKGROUND: Candida glabrata causes significant medical problems in immunocompromised patients. Many strains of this yeast are intrinsically resistant to azole antifungal agents, and treatment is problematic, leading to high morbidity and mortality rates in immunosuppressed individuals. The primary...

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Main Authors: Farahyar, Shirin, Zaini, Farideh, Kordbacheh, Parivash, Rezaie, Sassan, Safara, Mahin, Raoofian, Reza, Heidari, Mansour
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556022/
https://ncbi.nlm.nih.gov/pubmed/23351326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-21-1
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