Engineering Foot-and-Mouth Disease Viruses with Improved Growth Properties for Vaccine Development

BACKGROUND: No licensed vaccine is currently available against serotype A foot-and-mouth disease (FMD) in China, despite the isolation of A/WH/CHA/09 in 2009, partly because this strain does not replicate well in baby hamster kidney (BHK) cells. METHODOLOGY/PRINCIPAL FINDINGS: A novel plasmid-based...

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Detalhes bibliográficos
Main Authors: Zheng, Haixue, Guo, Jianhong, Jin, Ye, Yang, Fan, He, Jijun, Lv, Lv, Zhang, Kesan, Wu, Qiong, Liu, Xiangtao, Cai, Xuepeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555929/
https://ncbi.nlm.nih.gov/pubmed/23372840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055228
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