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Reversible Inhibition of Poliovirus RNA Synthesis In Vivo and In Vitro by Viral Products

In poliovirus-infected HeLa-S3 cells, the protease inhibitors tolylsulfonyl-phenylalanyl chloromethyl ketone and iodoacetamide cause an accumulation of large precursor proteins, and they block viral RNA synthesis most probably via these products. Viral RNA polymerase activity can, however, be extrac...

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Detalhes bibliográficos
Main Authors: Röder, Anton, Koschel, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC355590/
https://ncbi.nlm.nih.gov/pubmed/4371576
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