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Thermally Targeted Delivery of a c-Myc Inhibitory Polypeptide Inhibits Tumor Progression and Extends Survival in a Rat Glioma Model

Treatment of glioblastoma is complicated by the tumors’ high resistance to chemotherapy, poor penetration of drugs across the blood brain barrier, and damaging effects of chemotherapy and radiation to normal neural tissue. To overcome these limitations, a thermally responsive polypeptide was develop...

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Bibliografische gegevens
Hoofdauteurs: Bidwell, Gene L., Perkins, Eddie, Hughes, Joshua, Khan, Majid, James, Judy R., Raucher, Drazen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555869/
https://ncbi.nlm.nih.gov/pubmed/23372821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055104
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