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The Anaphase Promoting Complex Contributes to the Degradation of the S. cerevisiae Telomerase Recruitment Subunit Est1p

Telomerase is a multi-subunit enzyme that reverse transcribes telomere repeats onto the ends of linear eukaryotic chromosomes and is therefore critical for genome stability. S. cerevisiae telomerase activity is cell-cycle regulated; telomeres are not elongated during G1 phase. Previous work has show...

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Autores principales: Ferguson, Jenifer L., Chao, William Chong Hang, Lee, Ethan, Friedman, Katherine L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555863/
https://ncbi.nlm.nih.gov/pubmed/23372810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055055
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