The Kinetics of Plasmacytoid Dendritic Cell Accumulation in the Pancreas of the NOD Mouse during the Early Phases of Insulitis

In non-obese diabetic (NOD) mice that spontaneously develop autoimmune diabetes, plasmacytoid dendritic cells (pDCs) have a diabetes-promoting role through IFN-α production on one hand, while a diabetes-inhibiting role through indoleamine 2,3-dioxygenase (IDO) production on the other. Little is know...

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Autores principales: Welzen-Coppens, Jojanneke M. C., van Helden-Meeuwsen, Cornelia G., Leenen, Pieter J. M., Drexhage, Hemmo A., Versnel, Marjan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555833/
https://ncbi.nlm.nih.gov/pubmed/23372814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055071
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