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Endothelin-1 as a mediator and potential biomarker for interferon induced pulmonary toxicity
Endothelin-1 is a potent vasoconstrictor and a therapeutic target in pulmonary arterial hypertension. Endothelial cells are the physiological source of endothelin-1 but in vitro data from our group shows that interferons (IFNα, IFNβ or IFNγ) induce endothelin-1 in pulmonary vascular smooth muscle ce...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications & Media Pvt Ltd
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3555421/ https://ncbi.nlm.nih.gov/pubmed/23372935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.105039 |
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