Ent-11α-Hydroxy-15-oxo-kaur-16-en-19-oic-acid Inhibits Growth of Human Lung Cancer A549 Cells by Arresting Cell Cycle and Triggering Apoptosis

OBJECTIVE: To examine the apoptotic effect of ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F), a compound isolated from Pteris semipinnata L (PsL), in human lung cancer A549 cells. METHODS: A549 cells were treated with 5F (0–80 μg/ml) for different time periods. Cytotoxicity was examined using a...

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Detalhes bibliográficos
Main Authors: Li, Li, Chen, George G, Lu, Ying-nian, Liu, Yi, Wu, Ke-feng, Gong, Xian-ling, Gou, Zhan-ping, Li, Ming-yue, Liang, Nian-ci
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag Berlin Heidelberg 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555272/
https://ncbi.nlm.nih.gov/pubmed/23358391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11670-012-0109-8
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