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Short hairpin RNA-mediated MDR1 gene silencing increases apoptosis of human ovarian cancer cell line A2780/Taxol
OBJECTIVE: Recurrent ovarian cancer is often resistant to drugs such as paclitaxel. Short hairpin RNA (shRNA) targeting MDR1, a gene involved in the process of drug resistance, may be a promising strategy to overcome drug resistance. METHODS: Construction and identification of eukaryotic expression...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag Berlin Heidelberg
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3555269/ https://ncbi.nlm.nih.gov/pubmed/23359770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11670-012-0138-3 |
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