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Unveiling LOX-1 receptor interplay with nanotopography: mechanotransduction and atherosclerosis onset

Lectin-like ox-LDL receptors (LOX-1) play a crucial role in the ox-LDL–induced pathological transformation of vessel-wall components, a crucial early step in atherogenesis. LOX-1 dynamics is quantitatively investigated in human endothelial cells (HUVECs) exposed to environmental nanotopographies. We...

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Main Authors: Di Rienzo, Carmine, Jacchetti, Emanuela, Cardarelli, Francesco, Bizzarri, Ranieri, Beltram, Fabio, Cecchini, Marco
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555090/
https://ncbi.nlm.nih.gov/pubmed/23355954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01141
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