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Re-thinking cell cycle regulators: the cross-talk with metabolism

Analysis of genetically engineered mice deficient in cell cycle regulators, including E2F1, cdk4, and pRB, showed that the major phenotypes are metabolic perturbations. These key cell cycle regulators contribute to lipid synthesis, glucose production, insulin secretion, and glycolytic metabolism. It...

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Bibliografiska uppgifter
Huvudupphovsman: Fajas, Lluis
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555080/
https://ncbi.nlm.nih.gov/pubmed/23355973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00004
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