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Re-thinking cell cycle regulators: the cross-talk with metabolism

Analysis of genetically engineered mice deficient in cell cycle regulators, including E2F1, cdk4, and pRB, showed that the major phenotypes are metabolic perturbations. These key cell cycle regulators contribute to lipid synthesis, glucose production, insulin secretion, and glycolytic metabolism. It...

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Détails bibliographiques
Auteur principal: Fajas, Lluis
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555080/
https://ncbi.nlm.nih.gov/pubmed/23355973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00004
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