Formulation and evaluation of sublingual tablets containing Sumatriptan succinate

OBJECTIVE: Sumatriptan succinate is a selective 5-hydroxytryptamine-1 receptor agonist effective in the acute treatment of migraine headaches, having low bioavailability of about 15% orally due to first-pass metabolism. The purpose of this research was to mask the intensely bitter taste of Sumatript...

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Bibliographic Details
Main Authors: Prajapati, Shailesh T, Patel, Parth B, Patel, Chhagan N
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2012
Subjects:
Original Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555012/
https://ncbi.nlm.nih.gov/pubmed/23373008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.104400
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