Type 1 Inositol (1,4,5)-Trisphosphate Receptor Activates Ryanodine Receptor 1 to Mediate Calcium Spark Signaling in Adult Mammalian Skeletal Muscle

Functional coupling between inositol (1,4,5)-trisphosphate receptor (IP(3)R) and ryanodine receptor (RyR) represents a critical component of intracellular Ca(2+) signaling in many excitable cells; however, the role of this mechanism in skeletal muscle remains elusive. In skeletal muscle, RyR-mediate...

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Bibliografiska uppgifter
Huvudupphovsmän: Tjondrokoesoemo, Andoria, Li, Na, Lin, Pei-Hui, Pan, Zui, Ferrante, Christopher J., Shirokova, Natalia, Brotto, Marco, Weisleder, Noah, Ma, Jianjie
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554882/
https://ncbi.nlm.nih.gov/pubmed/23223241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.425975
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