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Potassium and Ionic Strength Effects on the Conformational and Thermal Stability of Two Aldehyde Dehydrogenases Reveal Structural and Functional Roles of K(+)-Binding Sites

Many aldehyde dehydrogenases (ALDHs) have potential potassium-binding sites of as yet unknown structural or functional roles. To explore possible K(+)-specific effects, we performed comparative structural studies on the tetrameric betaine aldehyde dehydrogenase from Pseudomonas aeruginosa (PaBADH) a...

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Détails bibliographiques
Auteurs principaux: Garza-Ramos, Georgina, Mújica-Jiménez, Carlos, Muñoz-Clares, Rosario A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554688/
https://ncbi.nlm.nih.gov/pubmed/23365686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054899
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